This content is strictly the opinion of Dr. Josh Axe and is for informational and educational purposes only. It is not intended to provide medical advice or to take the place of medical advice or treatment from a personal physician. All readers/viewers of this content are advised to consult their doctors or qualified health professionals regarding specific health questions. Neither Dr. Axe nor the publisher of this content takes responsibility for possible health consequences of any person or persons reading or following the information in this educational content. All viewers of this content, especially those taking prescription or over-the-counter medications, should consult their physicians before beginning any nutrition, supplement or lifestyle program.
Probi is continuously thriving to develop and investigate new possible indications where probiotics may have positive and efficient effects to improve health. We are science-driven, and investigate new possibilities to find the Next Generation Probiotics. This concept involves new bacterial strains that has never before been cultivated and used for health-purposes. 
B. Bifidum has also been shown to prevent intestinal pathogens or digestive disrupters from flourishing in the gut, essential in restoring the bacterial balance and optimizing digestion. Clinical research found it supports a significant reduction in IBS symptoms, an improvement in quality of life and even helps relieve occurrences of ulcerative colitis – a chronic inflammatory bowel disease. [1].
Make sure to keep them away from moisture and heat which can kill off some of the microbes. I recommend taking on an empty stomach, ideally right when you wake up. You should always store supplements in a cool, dark place but refrigeration is best. Most of the strains of probiotics are fragile and should be protected from heat- so refrigeration is ideal. I recommend the probiotic Gut Instinct from HUM Nutrition for transparency and high quality.

A popular dish in Japan consisting of fermented soybeans, natto contains the extremely powerful probiotic bacillus subtilis, which has been proven to bolster your immune system, support cardiovascular health and enhance digestion of vitamin K2. Natto can also contain vitamin B12, which is usually lacking in vegan diets. It’s also one of the highest plant-based proteins.


Many wondered whether probiotics could be therapeutic in other gastrointestinal disorders. Unfortunately, that doesn’t appear to be the case. Probiotics didn’t show a significant benefit for chronic diarrhea. Three reviews looked at how probiotics might improve Crohn’s disease, and none could find sufficient evidence to recommend their use. Four more reviews looked at ulcerative colitis, and similarly declared that we don’t have the data to show that they work. The same was true for the treatment of liver disease.

"This suggests that probiotics should not be universally given as a 'one-size-fits-all' supplement," study co-senior author Eran Elinav, an immunologist at the Weizmann Institute of Science in Israel, said in a statement. However, it may be possible to tailor probiotic treatments to the individual, based on the types of microbes already in his or her gut, as well as other factors, so that he or she gets the most benefit from probiotics, the researchers said.


Probiotic supplements and foods can play a major positive role in brain fog. Lactobacillus, in particular, can produce neurotransmitters used for brain neuron-to-neuron transmission to facilitate thinking. Probiotics can interact with the vagus nerve to the brain, with the enteric nervous system that can communicate with the brain, and with the brain via chemical messengers.
The right resident strains - quite a few probiotics on the market contain things like active yeasts or soil based organisms. While these ingredients may be helpful to some, if you want to optimize your gut health, you need to look for strains that are resident to the human gut like those from the Lactobacillus, Bifidobacterium, and Streptococcus families.

These are live microorganisms that will not provide the promised benefits if they don't remain alive. The manufacturer and consumer must pay close attention to the conditions of storage at which the particular microorganism will survive and the end of their shelf life. The potency will indicate the number of viable bacteria per dose, and the purity has to do with presence of contaminating or ineffective bacteria.
"The name itself is derived from the Latin 'pro-' meaning 'for' and the Greek '-biotic' meaning 'life,'" explains Jeannel Astarita, skincare expert and founder of Just Ageless NYC Wellness and Medspa. "Probiotics are the helpful bacteria that live primarily in your gut and play a crucial role in your overall health by fighting pathogens and yeast that lead to a weakened immune system."
In October 2013, the International Scientific Association for Probiotics and Prebiotics (ISAPP) organized a meeting of clinical and scientific experts on probiotics (with specialties in gastroenterology, pediatrics, family medicine, gut microbiota, microbiology of probiotic bacteria, microbial genetics, immunology, and food science) to reexamine the concept of probiotics. They define probiotics as "live microorganisms that, when administered in adequate amounts, confer a health benefit on the host." They also differentiated between products containing probiotics and those containing live or active cultures and established the following criteria:
Safety Warning In rare cases, some people may experience stomach upset due to Probiotics Cleansing Effect. This is positive sign as high potency probiotics removing waste or toxic substances from body. To avoid reaction, it's recommended to start with less dosage and slowly increase. Do not exceed recommended dose. Pregnant or nursing mothers, children under the age of 18, and individuals with a known medical condition should consult a physician before using this or any dietary supplement. May adversely affect existing medical conditions, including but not limited to: IBS (Irritable Bowel Syndrome), Gastritis, G.E.R.D. Please note: Probiotics may temporarily cause bloating, gas or gassy, stomach pain, hurt stomach or cramps (cramped, cramping), vomiting, nausea, diarrhea, constipation, changes in digestion, allergic reactions, heartburn, jitters, rashes, skin irritation, breakouts, headache, fatigue, changes in appetite, joints hurt, spike blood glucose, bad pains, terrible symptoms, tiredness, passed out or sick feeling or sickness. These possible side effects are rare and will vary from one person to another in occurrence and severity. This product does not contain Milk, Eggs, Soy, Wheat, Peanuts, Tree Nuts, Seafood, Fish. The Lactobacillus strain contained is grown on a dairy medium, but the dairy is removed in processing. People with severe allergies to dairy and those that are lactose intolerant should consult a medical professional before taking this product, as adverse reactions can occur. If for any reason you experience any adverse effects, immediately discontinue use of the product and consult with your doctor. Do not use if seal is missing or broken. Keep Out Of Reach of Children and Pets. KEEP OUT OF REACH OF CHILDREN. DO NOT USE IF SAFETY SEAL IS DAMAGED OR MISSING. STORE IN A COOL, DRY PLACE. Do not exceed recommended dose. Pregnant or nursing mothers, children under the age of 18 and individual with a known medical condition should consult a physician before using this or any other dietary supplement. Do not take this supplement if you are allergic to any of the listed ingredients. May adversely affect existing medical conditions, including but not limited to: G.E.R.D., IBS, Stomach Ulcer(s), asthma. Please note: Probiotics 60 Billion CFU may temporarily cause heartburn, gas, upset stomach, stomach cramps, stomach pain (hurt stomach), irritated stomach, burning stomach, acid reflux, bloating, constipation, increased chest congestion/mucus, insomnia, inflammation, fatigue, make your brain not feel right, nose bleeds, agitation, headaches, nausea, diarrhea (liquid stools, burning bowel movements, runs), intestinal issues, dry mouth, rash, itching, hives, dizziness, swollen tongue, vomiting, heart palpitations, fast heartbeat, unexpected issues or sickness. These possible side effects are rare and will vary from one person to another in occurrence and severity. If for any reason you experience any adverse effects, immediately discontinue use of the product and consult with your doctor. Do not use if seal is missing or broken. Keep Out Of Reach of Children and Pets. Caution: As with any dietary supplement, consult your healthcare practicioner before using this product, especially if you are pregnant, nursing, anticipate surgery, take medication on a regular basis or are otherwise under medical supervision. Keep out of reach of children. Do not use if safety seal is broken or missing. Contains no carriers, fillers, artificial colors . This product is labelled to United States standards and may differ from similar products sold elsewhere in its ingredients, labeling and allergen warnings
Since the bulk of your natural flora exists in your gut, it makes sense that this is the part of your body that feels it most when bacteria become imbalanced. Women, in particular, can experience all kinds of digestive problems, particularly during hormone fluctuations. These are just some of the digestive symptoms a high-quality probiotic can help reduce and even treat:
Tempeh is made with fermented soybeans or grains that have been molded into a cake-like form. The nuttier, tangier cousin to tofu can be sliced for sandwiches, tossed into stir-fries, or marinated and grilled. In addition to probiotics, tempeh contains about 15 grams of protein per half-cup and is a good source of iron. Plus, soy foods contain compounds that may help keep cholesterol in check, according to a study in The American Journal of Clinical Nutrition. Palmer likes to use tempeh in place of tofu in dishes like stir-fries, salads, and side dishes.

Popular probiotic foods include yogurt, kimchi, sauerkraut, and kombucha. While delicious, these foods don’t claim specific amounts of whatever microorganisms they may contain. By contrast, Probiotic All-Flora is optimally formulated with the right amounts of the right strains to deliver researched benefits. The label lists out the DNA-tested flora that make up that ideal 10 billion CFU in just one capsule daily. So probiotic supplements actually have more reliable strain benefits than probiotic foods.
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Jigsaw Essential Blend Probiotics uses five of the most researched (and effective) live strains to promote a healthy digestive system, restore flora after antibiotics use, and help with optimal vitamin absorption. Jigsaw products are also third-party certified, so you can rest assured that each batch is safe and pure. The bottom line? If you’re looking for a vegan-friendly formula — the capsules are made from HPMC (Hypromellose - Hydroxypropyl Methylcellulose), gelling agent (Gellan gum), and water — with a high CFU count, this product is for you. There are 90 capsules per bottle.


Afif Ghannoum said the key insight, one that he called groundbreaking, is that his father’s team found that fungi and microbes were cooperating in the construction of the plaques.  He said election microscope images show the filaments of the fungi being incorporated into the carbohydrate ‘armor’ that the bacteria start to secrete once enough individual cells have gathered at a certain location. Without the addition of the digestive enzyme to their product, he said that the plaques, once adhered to the intestinal wall, would be difficult to attack.
Bottom line: Probiotics are a promising field of research and may one day be used to treat or help prevent many disorders. But there’s not enough solid evidence to recommend their widespread use. Vague claims that probiotics "support good digestive health" are meaningless. Larger, longer and better studies are needed to test specific strains for specific conditions and to determine the proper doses and regimens.

Supplements play an important role when the diet is not adequate to supply our needs. In the case of probiotics, one's diet is the ideal source for probiotics. These are live bacteria and need to be carefully monitored, stored, and combined for the health benefits that one would be taking them for. At this time, supplements are not monitored in the U.S. the way that food or medication is. They fall under the Dietary Supplement Health and Education Act of 1994 (DSHEA). This requires that the dietary supplement or dietary ingredient manufacturer be responsible for ensuring that a dietary supplement or ingredient is safe before it is marketed. The only time that the U.S. Food and Drug Administration (FDA) may get involved is if action is needed to be taken against a manufacturer after the supplement is marketed and then found to be unsafe. This means that as much as we may know about probiotics, we can't be certain of the safety or content of the supplements available to us.


However, these naturally-occurring bacteria can easily become imbalanced causing a variety of symptoms from stomach upset to feminine health problems. Probiotics can help get things back on track. Taken in supplement form, probiotics are either live or dormant strains of the same bacteria that your body wants and needs to stay healthy. Over time, these supplements can restore your body’s natural bacteria and prevent some of the most common stomach symptoms, yeast infections, and even urinary tract infections.
Pure Therapeutics Power Probiotic 100B offers 100 billion CFUs of 4 powerful probiotic strains, including science darling, the HN019 strain of Bifidobacterium lactis. Since environmental factors, including moisture, oxygen and heat, can degrade the stability of your probiotics, Pure Therapeutics 100B is delivered in nitrogen-purged aluminum blister pacts, which ensure viability until the probiotic hits your system. No refrigeration is required.
The latest two-part research on probiotics was spearheaded by researchers at the Elinav Lab of Immunology at the Weizmann Institute of Science in Israel and colleagues at the Tel Aviv Medical Center. Eran Elinav served as a senior author for both studies along with Eran Segal and his lab of computational biologists who focus on health and disease related to microbiome, nutrition, genetics, and gene regulation. 
The other thing to remember is that these microorganisms are not all created equally. In fact, the genus, strain, and species all need to be the same for the results that found in the study to be the results that one hopes to achieve when taking it. For example, with the strain Lactobacillus rhamnosus GG, the genus is Lactobacillus, the species is rhamnosus, and the strain is GG. If any one of those is different in your supplement, you may not attain the same results.
If you suffer from recurrent urinary tract infections and are interested in giving cranberries a try, pay close attention to labels! As tasty as they may be, cranberry juice cocktails are chock full of sugar and very rarely include the D-Mannose your body needs. Instead, look for all-natural and organic cranberry juices or opt for cranberry extract pills if the pure juice isn’t exactly your cup of tea.
We’ll start with the headliner: the BIO-tract peral, which packs the equivalent of 75 billion CFUs into one tiny, filler-free, 5-billion CFUs pearl. The trick is in protecting those 5 billion CFUs over an 8 to 10-hour period, so they bypass your acidic stomach and reach your intestinal tract, alive and well, allowing you to experience the full and multitudinous benefits of plentiful and beneficial gut bacteria.
The recent buzz has helped bring probiotics into the main stream.  Due to being covered on major news sites and television personalities, probiotic supplements are now more accessible than ever.  The main benefits of probiotics begin within the gut and digestive system.  The gut plays such an important role, that the level of healthy bacteria in our bodies can actually alter our mood.  It’s true!  What we eat actually affects how we feel.  This is why the gut has been called our “second brain”.
The National Yogurt Association, who created this seal of approval, requires all yogurt manufacturers to include it on products that meet the standard of having a sufficient number of probiotics. The probiotics in store-bought yogurt need to meet this standard in order to be shelf-stable and reach your body alive. But even then, this standard isn’t all that useful in practice. The number just refers to the total number of live cultures and not the levels for each of those microbes. It’s possible, Taub-Dix says, that a product won’t have high enough levels of a certain probiotic to have any effect.

Called probiotics, these good bacteria help break down food, synthesize vitamins, prevent bacteria that cause illness from getting a foothold, and bolster immunity. Some studies suggest that as we get older, the number and variety of good bacteria in our bodies decline. So taking probiotic supplements to replenish them might seem like a no-brainer.
Because there's a huge variety of probiotic products available on the market, many people struggle to find the right one for them. "There are many different strains of bacteria in different combinations within different probiotic supplements," explains Brooke Scheller, a clinical and functional nutritionist. "For example, a probiotic may contain a single strain of bacteria or many. It may also contain other vitamins, minerals, or other ingredients that may tout health benefits," she says. There are many different dosages, delivery systems (powder, tablets, capsules), and formulations (refrigerated vs. shelf-stable), and some probiotics also contain prebiotics, which basically act as fertilizer for the probiotics. (Related: Why Your Probiotic Needs a Prebiotic Partner)
Billed as the most effective probiotic currently available on the market, Pro-25 combines 13 of the most powerful probiotic strains to deliver the most robust and well-rounded overall digestive health. Delayed-release capsules also protect live organisms from your stomach acid, delivering the right strains to the right location in your digestive system, ensuring maximum efficacy and benefits.
With the growing popularity of probiotics, there is a huge variety of supplements from which one can choose. The most important thing is to determine what type of probiotic microorganism you need for your condition. Do not just take the supplement that provides the most kinds of organisms. You need to do your research and be sure that there are scientific studies to support what you take. New research is emerging, so if you don't find what you need right now, keep looking. A doctor can help one decide if trying probiotics might be helpful for you and can advise you regarding the amount and type of probiotics that may be appropriate in your case.
Like some of the other probiotics we’ve reviewed, the HyperBiotics PRO-Women Probiotics with Cranberry Extract and D-Mannose do not need to be refrigerated in between uses. What sets this particular formula apart though is its longer shelf life made possible by the patented HyperBiotics ‘LiveBac’ manufacturing process. In fact, the HyperBiotics PRO-Women Probiotics formula can usually last for more than a year when stored in normal indoor conditions!
This Korean staple relies on lactic acid fermentation (also called lacto-fermentation) to turn cabbage or other vegetables into a spicy, pungent side dish that's packed with vitamin C. Order it at Korean restaurants or buy it in the refrigerated section of your grocery store (King's Kimchi is widely available at Walmart). For some guidance on making your own, turn to The Art of Fermentation ($23; amazon.com). Then, use it to spike veggie-laden rice bowls, top on soup, or serve alongside meat.
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