Research indicates that the gut and brain are in constant communication, and the health of your gut can have a big, supportive impact on your mental health and well-being.17 One reason is the role the gut microbiome plays in maintaining your hormones––in addition to oxytocin, your beneficial bacteria also support your levels of serotonin (the "happy hormone), and cortisol (which is associated with high stress levels).18 They also help encourage GABA, an important neurotransmitter that determines how your body responds to stress. When you support your microbiome with probiotics, it can help to keep everything balanced, but if it becomes unbalanced and unwanted bacteria take over, you can end up with a low mood and anxious thoughts.19
Selecting a multi-strain probiotic is also consistent with the theory that filling your gut with enough good bacteria outcompetes any bad bacteria for the same space and resources. In your gut, the more diversified the good bacteria, the harder it is for the baddies to gain a foothold. With all this in mind, we only looked at supplements containing multiple strains of bacteria.
​​​​​​AZO Complete Feminine BalanceTM is a daily probiotic supplement designed for the unique needs of women. Many everyday things can throw off your balance (stress, sex, pregnancy, aging, even medications! This product supports your feminine health and maintain a healthy pH so that you can own your day! It contains INTELLIFLORATM: a probiotic blend of four lactobacilli that are associated with vaginal health* (Lactobacillus crispatus LBV 88, Lactobacillus rhamnosus LBV 96, Lactobacillus jensenii LBV 116, and Lactobacillus gasseri LBV 150.)  The INTELLIFLORATM blend has been shown in clinical studies to help restore and maintain the healthy balance of the vaginal microbiota.*

"Although all of our probiotic-consuming volunteers showed probiotics in their stool, only some of them showed them in their gut, which is where they need to be," co-senior author Eran Segal, a computational biologist at the Weizmann Institute, said in the statement. "If some people resist and only some people permit them, the benefits of the standard probiotics we all take can't be as universal as we once thought."
"I recommend supplementing with the species lactobacillus and bifidobacterium, and there are different strains within those species that are each beneficial. Garden of Life and Align probiotics contain bacteria that help the gut microbiome and maintain digestive balance, and 1MD's Complete Probiotics Platinum is one of the best probiotics with over 50 billion live cultures that help with gut and digestive health."

Unfortunately, the U.S. has no federal standards for probiotic supplements. Therefore, you run the risk of purchasing a product without any guarantee that it contains its advertised probiotic strains, that the strains are alive, or that the product is free from unhealthy ingredients. Therefore, it may be best to choose a brand-name probiotic that has research backing their effectiveness. Here are some examples:


About 60 to 80 percent of our immune system lives in our gut. Imbalances in the gut’s microbiome (which is primarily made up of bacteria) lead to digestive issues, while many many other potential effects can be felt throughout the body—from feelings of fatigue to depression, thyroid dysfunction, autoimmunity, and a host of skin issues. Conditions like rosacea, psoriasis, eczema, and acne are really inflammatory conditions, and often a manifestation of something that is happening deeper within the body. When you fix the gut (which, depending on your health, might include getting rid of an infection like Candida, eating a clean diet, and taking a probiotic), skin issues often resolve as well.
Cardiovascular health is a major concern for men in Western societies. While some of the main challenges to maintaining a healthy heart (like excessive drinking and smoking) aren’t nearly as widespread as they once were, unwanted changes in heart function are still one of the most common reasons for men to need emergency medical care.1 But taking probiotics can help you keep your heart firing on all cylinders, even as you age.
To factor strain-specific benefits into our efficacy score, we referenced the information in these guides. Products were rewarded for containing strains on these lists. Additionally, measured levels of each strain were compared to what is thought to be effective based on these guides, and scores were scaled accordingly. In cases where products did not list strain-specific amounts, or their listed strains were not included in these guides, total measured CFUs were compared to a general effectiveness threshold of 1 billion CFUs cited by research published in the American Journal of Clinical Nutrition11.
Walk into any grocery store, and you will likely find more than a few “probiotic” products brimming with so-called beneficial bacteria that are supposed to treat everything from constipation to obesity to depression. In addition to foods traditionally prepared with live bacterial cultures (such as yogurt and other fermented dairy products), consumers can now purchase probiotic capsules and pills, fruit juices, cereals, sausages, cookies, candy, granola bars and pet food. Indeed, the popularity of probiotics has grown so much in recent years that manufacturers have even added the microorganisms to cosmetics and mattresses. 

While this feature contributes to the efficiency of the product, it is unclear whether this product is vegetarian like some of the other probiotics we reviewed. Therefore, if you have any dietary restrictions or needs, this may not be the best probiotic for you and may, in fact, cause additional stomach upset or irritation. It is however gluten-free.
DNA-testing matches identity at a foundational, genetic level, so you know you’re getting the exact strains listed. New Chapter’s DNA-testing also verifies that you receive the specific strains researched for specific benefits: our strains boost immune defenses and enhance digestion, including bowel regularity and reducing occasional gas, bloating, diarrhea & constipation.*
The other way that probiotics help is the impact that they have on our immune system. Some believe that this role is the most important. Our immune system is our protection against germs. When it doesn't function properly, we can suffer from allergic reactions, autoimmune disorders (for example, ulcerative colitis, Crohn's disease, and rheumatoid arthritis), and infections (for example, infectious diarrhea, H. pylori, skin infections, and vaginal infections). By maintaining the correct balance from birth, the hope would be to prevent these ailments. Our immune system can benefit anytime that balanced is restored, so it's never too late.
​​​​​​AZO Complete Feminine BalanceTM is a daily probiotic supplement designed for the unique needs of women. Many everyday things can throw off your balance (stress, sex, pregnancy, aging, even medications! This product supports your feminine health and maintain a healthy pH so that you can own your day! It contains INTELLIFLORATM: a probiotic blend of four lactobacilli that are associated with vaginal health* (Lactobacillus crispatus LBV 88, Lactobacillus rhamnosus LBV 96, Lactobacillus jensenii LBV 116, and Lactobacillus gasseri LBV 150.)  The INTELLIFLORATM blend has been shown in clinical studies to help restore and maintain the healthy balance of the vaginal microbiota.*
Probiotics may also be of use in maintaining urogenital health. Like the intestinal tract, the vagina is a finely balanced ecosystem. The dominant Lactobacilli strains normally make it too acidic for harmful microorganisms to survive. But the system can be thrown out of balance by a number of factors, including antibiotics, spermicides, and birth control pills. Probiotic treatment that restores the balance of microflora may be helpful for such common female urogenital problems as bacterial vaginosis, yeast infection, and urinary tract infection.
Some studies suggest that certain probiotic strains may also help in mild to moderate ulcerative colitis and possibly for bloating and gas in irritable bowel syndrome (IBS). Probiotic supplements, on the whole, “improve global symptoms, bloating, and flatulence in IBS,” by modifying the gut microbiome, according to a 2014 monograph from the American College of Gastroenterology. As IBS researchers said in a paper in Gastroenterology & Hepatology in 2015, “The concept of manipulating the microbiome is one of the most promising new ways in which to treat patients with IBS, but there is still much to learn.”
We also found strains linked to five other health benefits like weight loss and lowering cholesterol. We feature options for those cases below, but they aren’t top picks because those use cases aren’t as heavily researched as immune health or IBS relief. Still, chances are any probiotic supplement is going to make some improvement to your digestive health, so don’t be afraid to experiment.
While there a lot of great probiotics on the market to choose from our all-around top pick as the best probiotic for women is the Garden of Life Dr. Formulated Once Daily Women’s Probiotic. Backed by one of the most prominent names in the Human Microbiome industry, Garden of Life’s Dr. Formulated probiotic is ideal for newbies and seasoned probiotic users alike. We also love that this probiotic is shelf stable and designed to support complete digestive and feminine health.
We also found strains linked to five other health benefits like weight loss and lowering cholesterol. We feature options for those cases below, but they aren’t top picks because those use cases aren’t as heavily researched as immune health or IBS relief. Still, chances are any probiotic supplement is going to make some improvement to your digestive health, so don’t be afraid to experiment.
Unfortunately, many commercial brands don’t measure up. They are unstable in stomach acid. Quality control measures aren’t intact, including ensuring supplements have been handled correctly and maintain their freshness. Moisture slipping into probiotic supplements can reduce their efficacy. Companies that use bioshield capsules produce higher quality probiotic supplements that are able to endure the stomach acid, releasing their contents within the small intestine, where a more alkaline environment ensures the survival of the bacteria.
Self-dosing with bacteria isn't as outlandish as it might seem. An estimated 100 trillion microorganisms representing more than 500 different species inhabit every normal, healthy bowel. These microorganisms (or microflora) generally don't make us sick; most are helpful. Gut-dwelling bacteria keep pathogens (harmful microorganisms) in check, aid digestion and nutrient absorption, and contribute to immune function.
If you suffer from recurrent urinary tract infections and are interested in giving cranberries a try, pay close attention to labels! As tasty as they may be, cranberry juice cocktails are chock full of sugar and very rarely include the D-Mannose your body needs. Instead, look for all-natural and organic cranberry juices or opt for cranberry extract pills if the pure juice isn’t exactly your cup of tea.
Similar to yogurt, this fermented dairy product is a unique combination of milk and fermented kefir grains. Kefir has been consumed for well over 3,000 years, and the term kefir was started in Russia and Turkey and means “feeling good.” It is created by the fermentation of milk by the bacteria, and yeasts in kefir starter break down lactose in the milk — that’s why kefir may be suitable for those who are otherwise lactose-intolerant.
Having a healthy gut flora means an abundance for your health, digestion, wellbeing and even beauty! As we saw last week, there is ongoing communication between your GI and your brain known as the gut brain axis. This means a healthy gut can benefit the regularity of your digestion as well as cognitive function like mood and depression, and even the health and appearance of your skin.
For adult use only, this supplement also encourages a healthy intestinal system. It relieves gas, bloating, and constipation. Other wonderful aspects of this product include the following: It assists in nutrient absorption, it guarantees quality, and it has no artificial flavor, color, sweetener, lactose, milk, sugar, starch, preservatives, sodium, fish, yeast, wheat, gluten, or soy.
CFU: This is the number of "colony forming units" present in each dose, which are measured in the billions. And while more isn't always better, "you want at least 20 to 50 billion CFU," says Dr. Nazareth. Just for reference, a very high dose is 400 CFU, which most experts agree is not necessary unless your health care practitioner specifically recommends this for you. It's also important to check for the guaranteed CFU upon expiration, which should be listed clearly. "Some products only guarantee the CFU number at the time of manufacturing, therefore will be less potent by the time the product reaches your home," she says.
Sick of fighting off cold after cold? The Align Daily Immune Support Probiotic Supplement is a great way to give your immune system a boost while protecting your gut bacteria. Align is one of the most popular probiotic brands out there and is trusted by both doctors and nutritionists. The Daily Immune Support has Bifidobacterium lactis BB-12, a probiotic strain thought to be most beneficial to your immune health. It’s a lactic acid bacteria that can also help to fight lactose intolerance. This probiotic contains five billion CFUs (generally, most adults should take at least one billion CFUs in a probiotic) and is meant to be taken once a day.
“Highly recommend –There are quite a few probiotics manufactured specifically for women. Some are decent while others are not so good. For me, I require one on a daily basis to maintain my feminine health. When I try a new probiotic that is made specifically for women, it makes me a bit nervous because I will end up with yeast or bladder infection if it is not effective. With AZO, I am happy to report it is a great probiotic and highly recommend it to all women! It works great.” – Vicki
Overall, Enzymatic Therapy Acidophilus Pearls are a great daily probiotic supplement. They give you a ton of flexibility and is convenient since it doesn’t need to be refrigerated and can be taken with or without food! This probiotic makes on-the-go belly support a breeze. All in all, Enzymatic Therapy Acidophilus Pearls finally make it easy to travel with probiotics, are simple to take, and can give you the piece of mind that the money you’re spending on probiotics isn’t being wasted at the first sign of stomach acid.  Read the full review here… or click here to go buy it now!
To avoid those and other problems, I strongly recommend buying a professional brand from a reputable health care professional or other vendor who stands by their products and undergoes third-party testing. Some of these professional brands have created advanced technology that preserves a probiotic supplement’s survival on the shelf and in your gut.

Many studies have shown that probiotics reduce diarrhea associated with taking antibiotics in both adults and children. In fact, it is common for physicians and pharmacists to recommend eating a probiotic-fortified yogurt every day during a course of antibiotics to prevent diarrhea. More research is needed to determine which probiotics are associated with the greatest effect for specific antibiotics.
In the new study, the researchers analyzed information from 15 healthy volunteers who took either a probiotic product containing 11 strains of bacteria, or a placebo, for four weeks. The participants also underwent colonoscopies and upper endoscopies before they took the probiotics or the placebo, and again after the four-week treatment period. (An upper endoscopy looks at the upper part of the digestive tract.) During these procedures, the researchers took samples from inside participants' guts.
Lebwohl says IBS isn’t just about intestinal distress. For many IBS sufferers, it’s about the way our brain receives messages about pain. He describes the human colon as “almost reptilian” in the way that it contracts and relaxes throughout the day, but says these contractions are usually happening way below our threshold of consciousness, so we don’t even notice. In people with IBS, the neurotransmitters in our gut (yes, we have them in there too) may be sending severe distress signals to the brain about benign contractions happening in digestive tract.
When the digestive tract is healthy, it filters out and eliminates things that can damage it, such as harmful bacteria, toxins, chemicals, and other waste products. The healthy balance of bacteria assists with the regulation of gastrointestinal motility and maintenance of gut barrier function. Research has shown some benefits for the use of probiotics for infectious diarrhea, antibiotic-associated diarrhea, gut transit, IBS, abdominal pain and bloating, ulcerative colitis, Helicobacter pylori infection, nonalcoholic fatty liver disease (NAFLD), and necrotizing enterocolitis.
Microbes are tiny organisms (bacteria, viruses, parasites, or fungi) -- so tiny that millions can fit into the eye of a needle -- that are so powerful that an imbalance in the body is related to numerous diseases. These microorganisms can be found in almost every part of the human body, living on the skin, in the nose, and in the gut. There are trillions of these microorganisms in our bodies. They outnumber human cells by 10 to one, but due to their small size, they only make up 1%-3% of a body's total mass.
If your child has a history of stomach problems that medicine doesn’t seem to help, adding a probiotic to his or her diet can help. We love the OLLY Kids Happy Tummy Gummy Supplements because they offer complete probiotic support in a kid-friendly gummy form. Each gummy has a blend of prebiotic, probiotic, and peppermint to help soothe upset stomachs. They contain 500 million CFU of Bacillus coagulans. This container comes with 30 gummies (to be taken once a day) and is recommended for children 2 years and older.
Hi Joan, it’s possible, but not ideal because most pill form probiotic supplements are designed to be protected from stomach acid until the capsule reaches the intestines. It’s impossible to say how many probiotic microorganisms would survive by taking them this way, but certainly less than if you swallow the pills. I would recommend trying a probiotic gummy product or some other probiotic that comes in something other than pill form rather than opening up the capsules.
Overall, Garden of Life Primal Defense Ultra is one of my favorite probiotics! It uses a wide variety of potent probiotic strains that may help with daily digestion and specific stomach ailments. So it’s very flexible as far as probiotics are concerned. After personally testing out the product, my overall health felt improved, I wasn’t bloated, and I was digesting my food much better than normal.  Read the full review here… or click here to go buy it now!
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